All the unpredictability of the FA Cup came back to haunt Everton manager David Moyes at his former club Shrewsbury Town, with the Premiership big boys were humbled 2-1.
It was the much travelled Nigel Jemson who gave Shrewsbury a well deserved 39th minute lead and although second-half substitute Niclas Alexandersson restored level terms for the Merseysiders just before the hour, the Shrews were not to be denied, with Jemson nodding home the winner just 90 seconds from time as the FA Cup produced another famous giant killing.
Shrewsbury, seventh from bottom of Division Three, showed premier high-flyers Everton no respect and dominated the opening stages.
In the 12th minute it took a brilliant save from Everton's Richard Wright to prevent Jemson from opening the scoring - going full length to tip away a clever glancing header.
Although Everton created a number of openings as the half unfolded, the home side continued to hold sway and it was no more than they deserved when Jemson fired them ahead six minutes before the break.
After his strike partner, Luke Rodgers, had been fouled on the edge of the box, Jemson's sweetly struck free-kick beat Wright at his near post to give Shrewsbury the lead their first half pressure deserved.
Four minutes in to the second half referee Steve Dunne waived away loud home appeals for a penalty when Rodgers went sprawling in the box - and that decision looked crucial when Alexandersson levelled for Everton with an angled drive after 59 minutes.
Shrewsbury had the final say and in the 88th minute Jemson got the first and decisive touch to Ian Woan's curling free-kick as Shrewsbury pulled off one of the great Cup upsets.